About Probable ribonuclease ZC3H12D
Probable ribonuclease ZC3H12D (ZC3H12D) is a protein
from Homo sapiens identified by UniProt accession
A2A288, 527 residues long.
MolForge cross-references it against 0 known binders and
109 disease associations.
Target properties
| Protein name | Probable ribonuclease ZC3H12D |
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| UniProt accession | A2A288 |
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| Gene | ZC3H12D |
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| Organism | Homo sapiens |
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| Length | 527 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A2A288-F1 | alphafold | PREDICTED | 68.63 | — |
Amino-acid sequence (527 residues)
MEHPSKMEFF QKLGYDREDV LRVLGKLGEG ALVNDVLQEL IRTGSRPGAL EHPAAPRLVP RGSCGVPDSA QRGPGTALEE DFRTLASSLR PIVIDGSNVA MSHGNKETFS CRGIKLAVDW FRDRGHTYIK VFVPSWRKDP PRADTPIREQ HVLAELERQA VLVYTPSRKV HGKRLVCYDD RYIVKVAYEQ DGVIVSNDNY RDLQSENPEW KWFIEQRLLM FSFVNDRFMP PDDPLGRHGP SLSNFLSRKP KPPEPSWQHC PYGKKCTYGI KCKFYHPERP HHAQLAVADE LRAKTGARPG AGAEEQRPPR APGGSAGARA APREPFAHSL PPARGSPDLA ALRGSFSRLA FSDDLGPLGP PLPVPACSLT PRLGGPDWVS AGGRVPGPLS LPSPESQFSP GDLPPPPGLQ LQPRGEHRPR DLHGDLLSPR RPPDDPWARP PRSDRFPGRS VWAEPAWGDG ATGGLSVYAT EDDEGDARAR ARIALYSVFP RDQVDRVMAA FPELSDLARL ILLVQRCQSA GAPLGKP
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