About Dystrotelin
Dystrotelin (DYTN) is a protein
from Homo sapiens identified by UniProt accession
A2CJ06, 578 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | Dystrotelin |
|---|
| UniProt accession | A2CJ06 |
|---|
| Gene | DYTN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 578 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.05
- diet measurement · score 0.05
- episodic memory · score 0.04
- autosomal recessive hypophosphatemic rickets · score 0.03
- self reported educational attainment · score 0.03
- upper respiratory tract disorder · score 0.03
- body mass index · score 0.02
- Sepsis · score 0.01
- encephalitis · score 0.00
- nonpapillary renal cell carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A2CJ06-F1 | alphafold | PREDICTED | 69.32 | — |
Amino-acid sequence (578 residues)
MDPDKQDALN SIENSIYRTA FKLQSVQTLC QLDLIDSSLI QQVLLRPSFW EARKHSLSVQ QLSQALQELF QKAREENPGQ VHPRAPELTL SLLTTMYNSK GTGFLQLMPA AAALITLSGD SPLSKYRALF QLYAENSRGG YDSGPRMTRR VLRKLLTDLQ QIPTFVGESR ALCPVESATR SCFQGVLSPA IKEEKFLSWV QSEPPILLWL PTCHRLSAAE RVTHPARCTL CRTFPITGLR YRCLKCLNFD ICQMCFLSGL HSKSHQKSHP VIEHCIQMSA MQNTKLLFRT LRNNLLQGRC RKKEAARRQQ LLDQVNPKGV PHHAQARLLK KQLNQYKDKL QAIYTSQEER ICRFETRIHK LKTNQDSLWT KLQQIRRDLQ ARLQPPGPSS SSFQNVGNKV DHSSTEKVPK GGDYLQIKNA TEDASTGEPL PKLDEVDRSH RSHTNAEHAL RNPESPETTL HSTRAQSQTQ KMPQKVISAL PSYQEGLKQD IPKMVPAEMS SPALAAVEKK EAGNIKERKD ELEEEELQEL LSKLMDAFNL ETPSGPESSV NMDLYSGAQR VCRAFSALVD QIALPNLK
Explore Dystrotelin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets