T-cell receptor gamma alternate reading frame protein (TRGC1)

Homo sapiens — UniProt A2JGV3

Gene: TRGC1Homo sapiensSwissProt reviewed

About T-cell receptor gamma alternate reading frame protein

T-cell receptor gamma alternate reading frame protein (TRGC1) is a protein from Homo sapiens identified by UniProt accession A2JGV3, 58 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.

Target properties

Protein nameT-cell receptor gamma alternate reading frame protein
UniProt accessionA2JGV3
GeneTRGC1
OrganismHomo sapiens
Length58 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (103)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.31
  • neoplasm · score 0.02
  • Staphylococcus aureus infection · score 0.01
  • acute lymphoblastic leukemia · score 0.01
  • Rheumatoid arthritis · score 0.01
  • T-cell non-Hodgkin lymphoma · score 0.01
  • mycosis fungoides · score 0.01
  • Cutaneous T-cell lymphoma · score 0.01
  • atherosclerosis · score 0.01
  • cancer · score 0.01

3D Structure

Predicted structure for A2JGV3 is available from the AlphaFold Protein Structure Database.

Amino-acid sequence (58 residues)

MQMFPPSPLF FFLQLLKQSS RRLEHTFVFL RNFSLMLLRY IGKKRRATRF WDPRRGTP

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Quick facts

UniProtA2JGV3
GeneTRGC1
OrganismHomo sapiens
Length58
Binders0
Diseases103
View on UniProt