About Zinc finger protein 320
Zinc finger protein 320 (ZNF320) is a protein
from Homo sapiens identified by UniProt accession
A2RRD8, 509 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Zinc finger protein 320 |
| UniProt accession | A2RRD8 |
| Gene | ZNF320 |
| Organism | Homo sapiens |
| Length | 509 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.35
- platelet crit · score 0.24
- visual perception measurement · score 0.21
- mean corpuscular volume · score 0.20
- eosinophil count · score 0.19
- platelet count · score 0.10
- cystatin C measurement · score 0.07
- hepatocellular carcinoma · score 0.07
- blood phosphate measurement · score 0.07
- neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-A2RRD8-F1 | alphafold | PREDICTED | 68.72 | — |
Amino-acid sequence (509 residues)
MALSQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS SKCMMNTLSS TGQGNTEVIH TGTLQRQASY HIGAFCSQEI EKDIHDFVFQ WQEDETNDHE APMTEIKKLT SSTDRYDQRH AGNKPIKGQL ESRFHLHLRR HRRIHTGEKP YKCEECEKVF SCKSHLEIHR IIHTGEKPYK CKVCDKAFKH DSHLAKHTRI HRGDKHYTCN ECGKVFDQKA TLACHHRSHT GEKPYKCNEC GKTFSQTSHL VYHHRLHTGE KPYKCNECGK TFARNSVLVI HKAVHTAEKP YKCNECGKVF KQRATLAGHR RVHTGEKPYR CEECDKVFSR KSHLERHRRI HTGEKPYKCK VCDKAFRSDS RLAEHQRVHT GERPYTCNEC GKVFSTKAYL ACHQKLHTGE KLYECEECDK VYIRKSHLER HRRIHTGEKP HKCGDCGKAF NSPSHLIRHQ RIHTGQKSYK CHQCGKVFSL RSLLAEHQKI PFGDNCFKCN EYSKPSSIN
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