Protein HEATR9 (HEATR9)

Homo sapiens — UniProt A2RTY3

Gene: HEATR9Homo sapiensSwissProt reviewed

About Protein HEATR9

Protein HEATR9 (HEATR9) is a protein from Homo sapiens identified by UniProt accession A2RTY3, 570 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein nameProtein HEATR9
UniProt accessionA2RTY3
GeneHEATR9
OrganismHomo sapiens
Length570 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (21)

Diseases linked to this target (Open Targets).

  • platelet component distribution width · score 0.09
  • blood protein measurement · score 0.06
  • infection · score 0.06
  • infect · score 0.06
  • reticulocyte count · score 0.05
  • CCL5 measurement · score 0.05
  • influenza · score 0.05
  • viral disease · score 0.05
  • reticulocyte measurement · score 0.04
  • brucellosis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-A2RTY3-F1alphafoldPREDICTED71.05—

Amino-acid sequence (570 residues)

MAYEKSTDIS DVSRSMFLYP WLEYPDKTKE LRKAMAPVHL PLSCYQMPKE EFPPSPECWR QHPSKPNSVP YCYFKKPEIY THWHDLYDQR EEREAEKMLR KMRDDCRYIK EVHQTHIKMF HLPMSKLTIK SEMRSRPLEP TQDPLKWQRL RELTKSLESP REDEQFYAAQ ALGCLRISDK FVMEALQQVA QTGPEKVKYE AYRTLAILGC LNKHVIRALI KQLKEKNEGQ RMETLTGLRM ALNSWAAVSK DKRTQVGDEG KLVPVLQTLI KKSSSEASLE AALCLGFLRP CSNMVQEFLL QCLCQGLKTQ RMKALRMLVK VMHVHSAPVI KAILDQLCSS SVLEDRFEAT QMLKTIGLEQ IQAQGLEELT FNLLRRKTHN EPFLAVRQAV AQTVEELKLK PTMMNLVEAQ LMNPDATARQ EAVISLGVLG IRSPQVFHLL LDLLDAENHQ AVKKSLQETL ILCASIDPWI QNKLKNKVLS VYEAPKTNVK AEPTRFQKEP ENPEELTIQD FRLAKLNPLF IAKSITKVGQ KKTPAFPPCC SKPRKHRPQV IGPWQPRIKK QLRVLAEIAK

Explore Protein HEATR9 with MolForge

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Quick facts

UniProtA2RTY3
GeneHEATR9
OrganismHomo sapiens
Length570
Binders0
Diseases21
View on UniProt