About Homeobox protein HMX2
Homeobox protein HMX2 (HMX2) is a protein
from Homo sapiens identified by UniProt accession
A2RU54, 273 residues long.
MolForge cross-references it against 0 known binders and
70 disease associations.
Target properties
| Protein name | Homeobox protein HMX2 |
|---|
| UniProt accession | A2RU54 |
|---|
| Gene | HMX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 273 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (70)
Diseases linked to this target (Open Targets).
- sleep duration · score 0.29
- body height · score 0.22
- lung volume · score 0.21
- vital capacity · score 0.20
- alcohol consumption measurement · score 0.18
- serum urea measurement · score 0.18
- adolescent idiopathic scoliosis · score 0.18
- handedness · score 0.17
- chronotype measurement · score 0.17
- IGF-1 measurement · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A2RU54-F1 | alphafold | PREDICTED | 64.62 | — |
Amino-acid sequence (273 residues)
MGSKEDAGKG CPAAGGVSSF TIQSILGGGP SEAPREPVGW PARKRSLSVS SEEEEPDDGW KAPACFCPDQ HGPKEQGPKH HPPIPFPCLG TPKGSGGSGP GGLERTPFLS PSHSDFKEEK ERLLPAGSPS PGSERPRDGG AERQAGAAKK KTRTVFSRSQ VYQLESTFDM KRYLSSSERA CLASSLQLTE TQVKTWFQNR RNKWKRQLSA ELEAANMAHA SAQTLVSMPL VFRDSSLLRV PVPRSLAFPA PLYYPGSNLS ALPLYNLYNK LDY
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