About Protein FAM234B
Protein FAM234B (FAM234B) is a protein
from Homo sapiens identified by UniProt accession
A2RU67, 622 residues long.
MolForge cross-references it against 0 known binders and
68 disease associations.
Target properties
| Protein name | Protein FAM234B |
|---|
| UniProt accession | A2RU67 |
|---|
| Gene | FAM234B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 622 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (68)
Diseases linked to this target (Open Targets).
- body height · score 0.37
- bone density · score 0.32
- appendicular lean mass · score 0.31
- urate measurement · score 0.30
- serum albumin measurement · score 0.30
- total lipids in lipoprotein particles measurement · score 0.09
- heel bone mineral density · score 0.09
- bone quantitative ultrasound measurement · score 0.08
- breast cancer · score 0.07
- cholelithiasis · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A2RU67-F1 | alphafold | PREDICTED | 77.60 | — |
Amino-acid sequence (622 residues)
MATVLSRALK LPGKKSPDLG EYDPLTQADS DESEDDLVLN LQKNGGVKNG KSPLGEAPEP DSDAEVAEAA KPHLSEVTTE GYPSEPLGGL EQKAASSLVS YVRTSVFLLT LGISMILVLL CAFLIPCPPR DLHSTWSRHL GSQGGGDLSP LELADVNGDG LRDVLLSFVM SRNGSAVGVS RPAANLVCLS GMNGSTLWSS LLPEEARDIT CLELMPGSLA ETICLVTGTH KMLSAFNATS GKAIWTLNPN YLSNGTLAAP VVVLPDLDED GVRDLVVLAI GELQPDLCFL LVSGRTGNPV GRPVKYNIVG VGNLIGPQVY ITTNGAVYIL FGFGNIQAVA LRDIFVQAQN RDSSPPSLQI EEPEWEKRRS INLSELIDVY SDGVELLQMV KAPDSNCSNL LITTRQSLVL LRGQNLTPYW ALRLQGLRSQ PTPGYFTDDQ TLDFLLQIQD GVGMKKMMVV DGDSGSIVWS YRAPCHMKET PATSAVTSDQ KSVFLFWAEG LSAASPNSDI ILGTEPPSLH HLYLLHPAFP SILLDLANTT GTVTASEVGI NDLWKDAFYV TRTTGPSSEG HPAALVVSKL SLRWALMEGQ MAQLQESTPK IGRGELRRFL SRIKFVEAPY EI
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