About Colipase-like protein 1
Colipase-like protein 1 (CLPSL1) is a protein
from Homo sapiens identified by UniProt accession
A2RUU4, 121 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Colipase-like protein 1 |
|---|
| UniProt accession | A2RUU4 |
|---|
| Gene | CLPSL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 121 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.33
- eosinophil percentage of leukocytes · score 0.05
- eosinophil percentage of granulocytes · score 0.04
- reticulocyte measurement · score 0.04
- leukocyte count · score 0.03
- mean corpuscular volume · score 0.03
- reticulocyte count · score 0.03
- mean corpuscular hemoglobin concentration · score 0.02
- eosinophil count · score 0.02
- Immature Reticulocyte Fraction Measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A2RUU4-F1 | alphafold | PREDICTED | 78.90 | — |
Amino-acid sequence (121 residues)
MMLPQWLLLL FLLFFFLFLL TRGSLSPTKY NLLELKESCI RNQDCETGCC QRAPDNCESH CAEKGSEGSL CQTQVFFGQY RACPCLRNLT CIYSKNEKWL SIAYGRCQKI GRQKLAKKMF F
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