About Cadherin-like and PC-esterase domain-containing protein 1
Cadherin-like and PC-esterase domain-containing protein 1 (CPED1) is a protein
from Homo sapiens identified by UniProt accession
A4D0V7, 1026 residues long.
MolForge cross-references it against 0 known binders and
72 disease associations.
Target properties
| Protein name | Cadherin-like and PC-esterase domain-containing protein 1 |
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| UniProt accession | A4D0V7 |
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| Gene | CPED1 |
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| Organism | Homo sapiens |
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| Length | 1026 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (72)
Diseases linked to this target (Open Targets).
- bone density · score 0.48
- heel bone mineral density · score 0.47
- body height · score 0.43
- mean corpuscular volume · score 0.39
- mean reticulocyte volume · score 0.39
- radius bone mineral density · score 0.39
- lower face morphology measurement · score 0.37
- BMI-adjusted waist-hip ratio · score 0.37
- bone mineral content measurement · score 0.35
- grip strength measurement · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4D0V7-F1 | alphafold | PREDICTED | 72.86 | — |
Amino-acid sequence (1026 residues)
MVCRPVFPCR RRFCPRPFLV GLVVAICLFY QTLTLRGSRK LTAAAPGAVP HTSTETQASR CKKGFSQDKQ CFLLSGNAQE TRKVKESMET HFGSHGRRAI LYRPPFYSKT ELQLHQHILT QHGYTVVIAE ERLNAGLGPG LLEQGDLGSW DLLICLSSKK AEGTPCISKE VMCQLGLHQK ANRLPEIQQP LCRKEGLCQI VRRFPELQLP VSPSVCLDQG MQLKPSTSSH LLKTVKPRVW KPGDWSREQL NETTVLAPHE TIFRAEDLSV ILKAYVLVTS LTPLRAFIHS TGTVWNPPKK KRFTVKLQTF FETFLRASSP QQAFDIMKEA IGKLLLAAEV FSETSTLGPK TFHRCRFCFQ LLTFDIGYGS FMYPVVLQVH EHLNFQDYDN MDFEDQNTEE FLLNDTFNFL FPNESSLSIF SEIFQRLYRS DVFKGENYQK ELNQCLSLEE INSIMTFIKE LGSLGQFQLL FPSTTPGIQS LMHEFYDVAN PVGNPGSVLT QYWSLLNVFE QFQFMNKKTQ PHPLEWNSFT EDKNIEKPQV PFDAIENKKA AVPQIKNENK EIHCSDDENT PCHIKQIFTH PHLELNPDFH PKIKDYYCEV PFDVVTVTIG VETPKCLCKV HLYEQAGPSF ASYPLGLGMN KISIFVVDES PAHGETLITY KLTIYREDRP SLPLFEAFTA CGFVQDCGLL IHPEETCGLQ PISSDYIEAI LQSELKRCPS GDMKGQWIVP CLSCSDNRTC DWREITWQPH NCQYGVLTKP QLQQCLGGRK ILFIGDSTNR GIMYYLIERL NETLQEWQKV HGTKFYHNVN GGKTLISYSY YPQFWISPSL RPTFENALEH LLQRSRPLEN TGQTVLVVGG VQWLNSNHLQ IIHKVLKREN LLNILVIIKT LGIGFHLPVD GVHFLTQSEV QNLWKENLII LDTAKKHGYE VVDTFTITMG RYKEFLQGKC GCHFHEVVKS KLSKEYNFIK MKRSRNHIMG RYFSNQSKLQ QGTVTNFRSP YHVRGPINQV CSEILLSRMC ANKRTM
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