About WD repeat-containing protein 91
WD repeat-containing protein 91 (WDR91) is a protein
from Homo sapiens identified by UniProt accession
A4D1P6, 747 residues long.
MolForge cross-references it against 0 known binders and
34 disease associations.
Target properties
| Protein name | WD repeat-containing protein 91 |
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| UniProt accession | A4D1P6 |
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| Gene | WDR91 |
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| Organism | Homo sapiens |
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| Length | 747 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (34)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- aspartate aminotransferase measurement · score 0.32
- serum alanine aminotransferase measurement · score 0.32
- alkaline phosphatase measurement · score 0.30
- serum gamma-glutamyl transferase measurement · score 0.23
- monocyte count · score 0.08
- monocyte percentage of leukocytes · score 0.08
- mean platelet volume · score 0.05
- serum albumin measurement · score 0.05
- congenital afibrinogenemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4D1P6-F1 | alphafold | PREDICTED | 74.21 | — |
Amino-acid sequence (747 residues)
MAEAVERTDE LVREYLLFRG FTHTLRQLDA EIKADKEKGF RVDKIVDQLQ QLMQVYDLAA LRDYWSYLER RLFSRLEDIY RPTIHKLKTS LFRFYLVYTI QTNRNDKAQE FFAKQATELQ NQAEWKDWFV LPFLPSPDTN PTFATYFSRQ WADTFIVSLH NFLSVLFQCM PVPVILNFDA ECQRTNQVQE ENEVLRQKLF ALQAEIHRLK KEEQQPEEEE ALVQHKLPPY VSNMDRLGDS ELAMVCSQRN ASLSQSPRVG FLSSLLPQSK KSPSRLSPAQ GPPQPQSSAK KESFGGQGTK GKDPTSGAKD GKSLLSGLAT GESGWSQHRQ RRLQDHGKER KELFSTTTSQ CAEKKPEASG PEAEPCPELH TEPVEPLTRA SSAGPEGGGV RPEQPFIVLG QEEYGEHHSS IMHCRVDCSG RRVASLDVDG VIKVWSFNPI MQTKASSISK SPLLSLEWAT KRDRLLLLGS GVGTVRLYDT EAKKNLCEIN INDNMPRILS LACSPNGASF VCSAAAPSLT SQVDFSAPDI GSKGMNQVPG RLLLWDTKTM KQQLQFSLDP EPIAINCTAF NHNGNLLVTG AADGVIRLFD MQQHECAMSW RAHYGEVYSV EFSYDENTVY SIGEDGKFIQ WNIHKSGLKV SEYSLPSDAT GPFVLSGYSG YKQVQVPRGR LFAFDSEGNY MLTCSATGGV IYKLGGDEKV LESCLSLGGH RAPVVTVDWS TAMDCGTCLT ASMDGKIKLT TLLAHKA
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