Grifin (GRIFIN)

About Grifin

Grifin (GRIFIN) is a protein from Homo sapiens identified by UniProt accession A4D1Z8, 144 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	Grifin
UniProt accession	A4D1Z8
Gene	GRIFIN
Organism	Homo sapiens
Length	144 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.31
systolic blood pressure · score 0.27
diastolic blood pressure · score 0.27
reticulocyte measurement · score 0.26
hypertension · score 0.26
hematocrit · score 0.24
platelet count · score 0.23
cardiovascular disease · score 0.22
Immature Reticulocyte Fraction Measurement · score 0.21
heel bone mineral density · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A4D1Z8-F1	alphafold	PREDICTED	87.00	—

Amino-acid sequence (144 residues)

MAVQSKAFCA GGLAPGWKLL VQGHADSGED RFETNFLLET GDIAFHIKPR FSSATVVGNA FQYGRWGPEQ VSSIFPLAPG EPFEIEVSWD AEHFHVYAPE HKVLQFPCRQ RPLGATTRVR VLSDHCLAQV ELAKRGLSWG DRGY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards