About Metallo-beta-lactamase domain-containing protein 1
Metallo-beta-lactamase domain-containing protein 1 (MBLAC1) is a protein
from Homo sapiens identified by UniProt accession
A4D2B0, 266 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Metallo-beta-lactamase domain-containing protein 1 |
|---|
| UniProt accession | A4D2B0 |
|---|
| Gene | MBLAC1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- age at menarche · score 0.04
- hemoglobin measurement · score 0.03
- mean corpuscular hemoglobin · score 0.02
- hematocrit · score 0.02
- cancer · score 0.01
- cardiovascular disease · score 0.00
- Neurodevelopmental delay · score 0.00
- Parkinson disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4D2B0-F1 | alphafold | PREDICTED | 89.13 | — |
Amino-acid sequence (266 residues)
MRTEPLCGAS PLLVPGDPYS VVVLLQGYAE PEGVGDAVRA DGSVTLVLPQ TRGPASSHRE SPRGSGGAEA ALEEAARGPI LVDTGGPWAR EALLGALAGQ GVAPGDVTLV VGTHGHSDHI GNLGLFPGAA LLVSHDFCLP GGRYLPHGLG EGQPLRLGPG LEVWATPGHG GQRDVSVVVA GTALGTVVVA GDVFERDGDE DSWQALSEDP AAQERSRKRV LVVADVVVPG HGPPFRVLRE ASQPETEGGG NSQQEPVVGD EEPALH
Explore Metallo-beta-lactamase domain-containing protein 1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets