About Olfactory receptor 2A25
Olfactory receptor 2A25 (OR2A25) is a protein
from Homo sapiens identified by UniProt accession
A4D2G3, 310 residues long.
MolForge cross-references it against 0 known binders and
6 disease associations.
Target properties
| Protein name | Olfactory receptor 2A25 |
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| UniProt accession | A4D2G3 |
|---|
| Gene | OR2A25 |
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| Organism | Homo sapiens |
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| Length | 310 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (6)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- low grade glioma · score 0.18
- breast carcinoma · score 0.04
- colorectal adenocarcinoma · score 0.04
- non-small cell lung carcinoma · score 0.03
- glioblastoma multiforme · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4D2G3-F1 | alphafold | PREDICTED | 84.84 | — |
Amino-acid sequence (310 residues)
MGGNQTSITE FLLLGFPIGP RIQMLLFGLF SLFYIFILLG NGTILGLISL DSRLHTPMYF FLSHLAVVDI ACACSTVPQM LVNLLHPAKP ISFAGCMTQM FLFLSFAHTE CLLLVVMSYD RYVAICHPLR YSTIMTWKVC ITLALTSWIL GVLLALVHLV LLLPLSFCGP QKLNHFFCEI MAVLKLACAD THINEVMVLA GAVSVLVGAF FSTVISYVHI LCAILKIQSG EGCQKAFSIC SSHLCVVGLF YGTAIIMYVE PQYESPKEQK KYLLLFHSLF NPMLNPLIYS LRNKEVQGTL KRMLEKKRTS
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