About cTAGE family member 9
cTAGE family member 9 (CTAGE9) is a protein
from Homo sapiens identified by UniProt accession
A4FU28, 777 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | cTAGE family member 9 |
|---|
| UniProt accession | A4FU28 |
|---|
| Gene | CTAGE9 |
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| Organism | Homo sapiens |
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| Length | 777 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (22)
Diseases linked to this target (Open Targets).
- blood phosphate measurement · score 0.27
- alkaline phosphatase measurement · score 0.09
- anxiety · score 0.08
- hypertriglyceridemia 2 · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.05
- pancreatic triacylglycerol lipase deficiency · score 0.05
- homozygous familial hypercholesterolemia · score 0.04
- Combined hyperlipidemia · score 0.04
- thyroid hormone metabolism, abnormal, 2 · score 0.04
- Fish-eye disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4FU28-F1 | alphafold | PREDICTED | 68.45 | — |
Amino-acid sequence (777 residues)
MEEPGATPQP YLGLVLEELG RVVAALPESM RPDENPYGFP SELVVCAAVI GFFVVLLFLW RSFRSVRSRL YVGREQKLGA TLSGLIEEKC KLLEKFSLIQ KEYEGYEVES SLEDASFEKA AAEEARSLEA TCEKLSRSNS ELEDEILCLE KDLKEEKSKH SQQDELMADI SKSIQSLEDE SKSLKSQIAE AKIICKTFKM SEERRAIAIK DALNENSQLQ TSHKQLFQQE AEVWKGQVSE LNKQKITFED SKVHAEQVLN DKENHIKTLT GHLPMMKDQA AVLEEDTTDD DNLELKVNSQ WENGANLDDP PKGALKKLIH AAKLNVSLKS LEGERNHIII QLSEVDKTKE ELTEHIKNLQ TQQASLQSEN IYFESENQKL QQKLKIMTEF YQENEMKLYR KLTVEENYRI EEEEKLSRVE EKISHATEEL ETYRKLAKDL EEELERTVHF YQKQVISYEK RGHDNWLAAR TAERNLSDLR KENAHNKQKL TERELKFELL EKDPNALDVS NTAFGREHSP CSPSPLGRPS SETRAFPSPQ TLLEDPLRLS PVLPGGGGRG PSSPGNPLDH QITNERGEPS YDRLIDPHRA PSDTGSLSSP VEQDRRMMFP PPGQSYPDST LPPQREDRFY SNSERLSGPA EPRSFKMTSL DKMDRSMPSE MESSRNDAKD DLGNLNVPDS SLPAENEATG PGLIPPPLAP ISGPLFPVDT RGPFMRRGPP FPPPPPGTMF GASRGYFPPR DFPGPPHAPF AMRNIYPPRG LPPYLHPRPG FYPNPTF
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