About Solute carrier family 35 member F4
Solute carrier family 35 member F4 (SLC35F4) is a protein
from Homo sapiens identified by UniProt accession
A4IF30, 521 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Solute carrier family 35 member F4 |
| UniProt accession | A4IF30 |
| Gene | SLC35F4 |
| Organism | Homo sapiens |
| Length | 521 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.31
- protein measurement · score 0.30
- mathematical ability · score 0.24
- drug use measurement · score 0.13
- neurofibrillary tangles measurement · score 0.09
- gut microbiome measurement · score 0.09
- taxonomic microbiome measurement · score 0.09
- lymphocyte count · score 0.03
- body height · score 0.03
- breast carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-A4IF30-F1 | alphafold | PREDICTED | 66.94 | — |
Amino-acid sequence (521 residues)
MDELLLDLFH KLTSGRQLAA GNGLCGISHK EQEVWKPGHN ILVKMRKEDK SLVWLIHSTL ARYTQVTNFL GTSRSSVTRC KPGANCPSSH SGISRQLSPL SVTEDSSAPI LELQNQGSSG VCGHRVERQN RSADDGTQTH SENSSQENRI KARCLSCTSM VLKGIWGLLI ILSVSSSWVG TTQIVKITYK NFYCPFFMTW FSTNWNIMFF PVYYSGHLAT AQEKQSPMKK FRECSRIFGE DGLTLKLFLK RTAPFSILWT LTNYLYLLAL KKLTATDVSA LFCCNKAFVF LLSWIVLKDR FMGVRIVAAI MAITGIVMMA YADNFHADSI IGVAFAVGSA STSALYKVLF KMFLGSANFG EAAHFVSTLG FFNLIFISFT PVILYFTKVE HWSSFAALPW GCLCGMAGLW LAFNILVNVG VVLTYPILIS IGTVLSVPGN AAVDLLKQEV IFNVVRLAAT IIICIGFLLM LLPEEWDEIT LRFINSLKEK KSEEHVDDVT DPSIHLRGRG RANGTVSIPL A
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