About Cilia- and flagella-associated protein 90
Cilia- and flagella-associated protein 90 (CFAP90) is a protein
from Homo sapiens identified by UniProt accession
A4QMS7, 147 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Cilia- and flagella-associated protein 90 |
|---|
| UniProt accession | A4QMS7 |
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| Gene | CFAP90 |
|---|
| Organism | Homo sapiens |
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| Length | 147 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.22
- self reported educational attainment · score 0.14
- fasting blood insulin measurement · score 0.12
- bipolar disorder · score 0.11
- HbA1c measurement · score 0.11
- attention deficit hyperactivity disorder · score 0.10
- body height · score 0.10
- adolescent idiopathic scoliosis · score 0.10
- PHF-tau measurement · score 0.09
- mean corpuscular hemoglobin · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A4QMS7-F1 | alphafold | PREDICTED | 75.43 | — |
Amino-acid sequence (147 residues)
MEDDEEETTA STLRGKPRPP PVSAQSAFSY IPPRRLDPKE HSYYYRPART GIISLYDCIF KRRLDYDQKL HRDDREHAKS LGLHVNEEEQ ERPVGVLTSS VYGKRINQPI EPLNRDFGRA NHVQADFYRK NDIPSLKEPG FGHIAPS
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