About Ankyrin repeat domain-containing protein 62
Ankyrin repeat domain-containing protein 62 (ANKRD62) is a protein
from Homo sapiens identified by UniProt accession
A6NC57, 917 residues long.
MolForge cross-references it against 0 known binders and
5 disease associations.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 62 |
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| UniProt accession | A6NC57 |
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| Gene | ANKRD62 |
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| Organism | Homo sapiens |
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| Length | 917 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (5)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- DNA methylation · score 0.03
- hematocrit · score 0.02
- Crohn's disease · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NC57-F1 | alphafold | PREDICTED | 75.29 | — |
Amino-acid sequence (917 residues)
MEVRGSFLAA CRRRMATWRK NRDKDGFSNP GYRVRQKDLG MIHKAAIAGD VNKVMESILL RLNDLNDRDK KNRTALLLAC AHGRPGVVAD LVARKCQLNL TDSENRTALI KAVQCQEEVC ASILLEHGAN PNVRDMYGNT ALHYAIDNEN ISMARKLLAY GADIEARSQD GHTSLLLAVN RKKEQMVAFL LKKKPDLTAI DNFGRTALIL AARNGSTSVV YQLLQHNIDV FCQDISGWTA EDYAVASKFQ AIRGMISEYK ANKRCKSLQN SNSEQDLEMT SEGEQERLEG CESSQPQVEE KMKKCRNKKM EVSRNVHADD SDNYNDDVDE LIHKIKNRKP DNHQSPGKEN GEFDRLARKT SNEKSKVKSQ IYFTDDLNDI SGSSEKTSED DELPYSDDEN FMLLIEQSGM ECKDFVSLSK SKNATAACGR SIEDQKCYCE RLKVKFQKMK NNISVLQKVL SETDKTKSQS EHQNLQGKKK LCNLRFILQQ QEEERIKAEE LYEKDIEELK IMEEQYRTQT EVKKQSKLTL KSLEVELKTV RSNSNQNFHT HERERDLWQE NHLMRDEIAR LRLEIDTIKH QNQETENKYF KDIEIIKENN EDLEKTLKRN EEALTKTITR YSKELNVLMD ENTMLNSELQ KEKQSMSRLE TEMESYRCRL AAALCDHDQR QSSKRDLQLA FQSTVNEWCH LQEDTNSHIQ ILSQQLSKAE STSSGLETEL HYEREALKEK TLHIEHMQGV LSRTQRRLED IEHMYQNDQP ILEKYVRKQQ SVEDGLFQLQ SQNLLYQQQC NDARKKADNQ EKTIINIQVK CEDTVEKLQA ECRKLEENNK GLMKECTLLK ERQCQYEKEK EEREVVRRQL QREVDDALNK QLLLEAMLEI SSERRINLED EAQSLKKKLG QMRSQVCMKL SMSTVTL
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