About phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein
phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein (PINLYP) is a protein
from Homo sapiens identified by UniProt accession
A6NC86, 204 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein |
|---|
| UniProt accession | A6NC86 |
|---|
| Gene | PINLYP |
|---|
| Organism | Homo sapiens |
|---|
| Length | 204 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- low density lipoprotein cholesterol measurement · score 0.18
- body height · score 0.10
- appendicular lean mass · score 0.10
- apolipoprotein B measurement · score 0.05
- forced expiratory volume · score 0.03
- calcium measurement · score 0.03
- viral disease · score 0.01
- infect · score 0.01
- infection · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NC86-F1 | alphafold | PREDICTED | 90.60 | — |
Amino-acid sequence (204 residues)
MRLSRRPETF LLAFVLLCTL LGLGCPLHCE ICTAAGSRCH GQMKTCSSDK DTCVLLVGKA TSKGKELVHT YKGCIRSQDC YSGVISTTMG PKDHMVTSSF CCQSDGCNSA FLSVPLTNLT ENGLMCPACT ASFRDKCMGP MTHCTGKENH CVSLSGHVQA GIFKPRFAMR GCATESMCFT KPGAEVPTGT NVLFLHHIEC THSP
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