Microtubule-associated protein 1 light chain 3 beta…

About Microtubule-associated protein 1 light chain 3 beta 2

Microtubule-associated protein 1 light chain 3 beta 2 (MAP1LC3B2) is a protein from Homo sapiens identified by UniProt accession A6NCE7, 125 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Microtubule-associated protein 1 light chain 3 beta 2
UniProt accession	A6NCE7
Gene	MAP1LC3B2
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

monocyte count · score 0.33
hair color · score 0.32
monocyte percentage of leukocytes · score 0.24
PHF-tau measurement · score 0.23
granulocyte percentage of myeloid white cells · score 0.21
pneumonia · score 0.02
neoplasm · score 0.01
nonpapillary renal cell carcinoma · score 0.00
hepatocellular carcinoma · score 0.00
paralytic poliomyelitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NCE7-F1	alphafold	PREDICTED	91.74	—

Amino-acid sequence (125 residues)

MPSEKTFKQR RTFEQRVEDV RLIREQHPTK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELIKIIRRR LQLNANQAFF LLVNGHSMVS VSTPISEVYE SEKDEDGFLY MVCASQETFG MKLSV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Microtubule-associated protein 1 light chain 3 beta 2 (MAP1LC3B2)