Tripartite motif-containing protein 43B (TRIM43B)

About Tripartite motif-containing protein 43B

Tripartite motif-containing protein 43B (TRIM43B) is a protein from Homo sapiens identified by UniProt accession A6NCK2, 446 residues long. MolForge cross-references it against 0 known binders and 0 disease associations.

Target properties

Protein name	Tripartite motif-containing protein 43B
UniProt accession	A6NCK2
Gene	TRIM43B
Organism	Homo sapiens
Length	446 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NCK2-F1	alphafold	PREDICTED	88.42	—

Amino-acid sequence (446 residues)

MDSDFSHAFQ KELTCVICLN YLVDPVTICC GHSFCRPCLC LSWEEAQSPA NCPACREPSP KMDFKTNILL KNLVTIARKA SLWQFLSSEK QICGTHRQTK KMFCDMDKSL LCLLCSNSQE HGAHKHYPIE EAAEEDREKL LKQMRILWKK IQENQRNLYE ERRTAFLLRG DVVLRAQMIR NEYRKLHPVL HKEEKQHLER LNKEYQEIFQ QLQRSWVKMD QKSKHLKEMY QELMEMCHKP EVELLQDLGD IVARSESVLL HMPQPVNPEL TAGPITGLVY RLNRFRVEIS FHFEVTNHNI RLFEDVRSWM FRRGPLNSDR SDYFAAWGAR VFSFGKHYWE LDVDNSCDWA LGVCNNSWIR KNSTMVNSED IFLLLCLKVD NHFNLLTTSP VFPHYIEKPL GRVGVFLDFE SGSVSFLNVT KSSLIWSYPA GSLTFPVRPF FYTGHR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards