About Leucine-rich colipase-like protein 1
Leucine-rich colipase-like protein 1 (LRCOL1) is a protein
from Homo sapiens identified by UniProt accession
A6NCL2, 159 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Leucine-rich colipase-like protein 1 |
|---|
| UniProt accession | A6NCL2 |
|---|
| Gene | LRCOL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 159 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- total cholesterol measurement · score 0.25
- platelet count · score 0.07
- low density lipoprotein cholesterol measurement · score 0.07
- optic cup area measurement · score 0.06
- prostate carcinoma · score 0.06
- health study participation · score 0.05
- hepatocellular carcinoma · score 0.05
- lymphocyte count · score 0.04
- body height · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NCL2-F1 | alphafold | PREDICTED | 81.69 | — |
Amino-acid sequence (159 residues)
MAGPGWTLLL LLLLLLLLGS MAGYGPQKKL NLSHKGIGEP CRRHEECQSN CCTINSLAPH TLCTPKTIFL QCLPWRKPNG YRCSHDSECQ SSCCVRNNSP QELCTPQSVF LQCVPWRKPN GDFCSSHQEC HSQCCIQLRE YSPFRCIPRT GILAQCLPL
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