About Protein FAM83G
Protein FAM83G (FAM83G) is a protein
from Homo sapiens identified by UniProt accession
A6ND36, 823 residues long.
MolForge cross-references it against 0 known binders and
88 disease associations.
Target properties
| Protein name | Protein FAM83G |
|---|
| UniProt accession | A6ND36 |
|---|
| Gene | FAM83G |
|---|
| Organism | Homo sapiens |
|---|
| Length | 823 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (88)
Diseases linked to this target (Open Targets).
- Palmoplantar keratoderma · score 0.18
- uncombable hair syndrome · score 0.10
- ringed hair disease · score 0.09
- 1,5 anhydroglucitol measurement · score 0.09
- pili bifurcati · score 0.07
- hypotrichosis simplex · score 0.06
- wooly hair, autosomal recessive 3 · score 0.06
- epidermolytic palmoplantar keratoderma, 1 · score 0.06
- pili torti · score 0.06
- primary familial polycythemia due to EPO receptor mutation · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6ND36-F1 | alphafold | PREDICTED | 59.01 | — |
Amino-acid sequence (823 residues)
MAFSQVQCLD DNHVNWRSSE SKPEFFYSEE QRLALEALVA RGRDAFYEVL KRENIRDFLS ELELKRILET IEVYDPGSED PRGTGPSQGP EDNGVGDGEE ASGADGVPIE AEPLPSLEYW PQKSDRSIPQ LDLGWPDTIA YRGVTRASVY MQPPIDGQAH IKEVVRKMIS QAQKVIAVVM DMFTDVDIFK DLLDAGFKRK VAVYIIVDES NVKYFLHMCE RACMHLGHLK NLRVRSSGGT EFFTRSATKF KGALAQKFMF VDGDRAVCGS YSFTWSAART DRNVISVLSG QVVEMFDRQF QELYLMSHSV SLKGIPMEKE PEPEPIVLPS VVPLVPAGTV AKKLVNPKYA LVKAKSVDEI AKISSEKQEA KKPLGLKGPA LAEHPGELPE LLPPIHPGLL HLERANMFEY LPTWVEPDPE PGSDILGYIN IIDPNIWNPQ PSQMNRIKIR DTSQASAQHQ LWKQSQDSRP RPEPCPPPEP SAPQDGVPAE NGLPQGDPEP LPPVPKPRTV PVADVLARDS SDIGWVLELP KEEAPQNGTD HRLPRMAGPG HAPLQRQLSV TQDDPESLGV GLPNGLDGVE EEDDDDYVTL SDQDSHSGSS GRGPGPRRPS VASSVSEEYF EVREHSVPLR RRHSEQVANG PTPPPRRQLS APHITRGTFV GPQGGSPWAQ SRGREEADAL KRMQAQRSTD KEAQGQQFHH HRVPASGTRD KDGFPGPPRY RSAADSVQSS TRNAGPAMAG PHHWQAKGGQ VPRLLPDPGS PRLAQNARPM TDGRATEEHP SPFGIPYSKL SQSKHLKART GGSQWASSDS KRRAQAPRDR KDP
Explore Protein FAM83G with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets