About WD repeat-containing protein 97
WD repeat-containing protein 97 (WDR97) is a protein
from Homo sapiens identified by UniProt accession
A6NE52, 1622 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | WD repeat-containing protein 97 |
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| UniProt accession | A6NE52 |
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| Gene | WDR97 |
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| Organism | Homo sapiens |
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| Length | 1622 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (15)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.26
- mean corpuscular hemoglobin · score 0.23
- blood metabolite measurement · score 0.22
- mean corpuscular hemoglobin concentration · score 0.21
- eosinophil count · score 0.21
- BMI-adjusted waist circumference · score 0.20
- mean reticulocyte volume · score 0.18
- type 2 diabetes mellitus · score 0.14
- serum metabolite measurement · score 0.13
- metabolite measurement · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NE52-F1 | alphafold | PREDICTED | 62.28 | — |
Amino-acid sequence (1622 residues)
MEAEVWEAEG YNLVLDSDLY DADGYDVPDP GLLTEKNELT FTEPSQVLPF LTSSQQWQSL TPRARARRLW LLLRTSLHEV VEKEKRAELR AARLTHGLEP LRRLEVAAGL RSVAQDPVGG RFVVLDGAGR LHLHKEDGWA QETLLAPVRL TGLVTVLGPL GAVGRFVGWG PAGLAILRPN LSLLWLSEQG VGRAPGWAPT CCLPVPDLRL LLVAEMNSSL ALWQFRSGGR RLVLRGSALH PPPSPTGRLM RLAVAPVPPH HVLRCFAAYG SAVLTFDLHA WTLVDVRRDL HKTTISDLAY CEEVEAMVTA SRDSTVKVWE ADWQIRMVFV GHTGPVTAMT VLPNTTLVLS ASQDGTLRTW DLQAAAQVGE VALGFWGQDK LSRRVGRLLA PVRPGWPVLS LCASSMQLWR VRELYSPLAQ LPAKVLHVQV APALPAPAHQ SLPTRLVCAC ADGSVYLLSA ATGRIVSSLL LEPEDCAAAV AYCLPREALW LLTRAGHLVR ANAARCPMSV LHRVCPPPPP APQPCCLHLY SHLTDLEGAF SSWEIVRQHW GELRCSSVAC AWKNKNRYLP VVGHTDGTLS VLEWLSSKTV FQTEAHSPGP VVAIASTWNS IVSSGGDLTV KMWRVFPYAE ESLSLLRTFS CCYPAVALCA LGRRVTAGFE DPDSATYGLV QFGLGDSPRL DHRPQDDPTD HITGLCCCPT LKLYACSSLD CTVRIWTAEN RLLRLLQLNG APQALAFCSN SGDLVLALGS RLCLVSHRLY LPTSYLVKKM CRKAPDVVDD PPLPLMSQES LTSAQLQRLT NLHGAASLSE ALSLIHRRRA TSQHLVPKED LDAIVARDRD LQQLRLGLVV PAAQPPPSWQ QRQEGFDNYL RLIYGSGLLG MQSGRGSQQW SAGTLRVERE TRDVCAVPQA AHCLARAEVS TAAQTVPTAL SPQDLGALGQ HFSQSPRVTV PIPPTHRRVH SKASQLLARS SLSHYLGISL DLQLQLEQLR GRTTMALDLP SSHLQCRIPL LPKRWDKEPL SSLRGFFPAT VQPHKHCLRP ICFPGYVPNS AVLQQMWLNA EPGASQDALW LWRPRPSQTQ WQRKLLQWMG EKPGEEGEED KKEEEEEKED EELDWALASL SPHSNQQLDS WELEDQSAVD WTQEPRRRSC KVARTHPHPW HRHGSLLLDE HYGHLPKFLH FFIYQTWFKK LFPIFSLQAY PEAGTIEGLA SLLVALLEKT TWVDRVHILQ VLLRLLPNMS SDLQGQLQGL LVHLLNLDQP PSLQDQTQKK FVILALQLLL ACSLESRDVV LELMSYFLYS PVHCRPELKK LLHGLGLQDP EGFLFKEMMT WVQGPDLDSK AGLRTCCHQK LEDMIQELQE TPSQTSVVSG APTRASVIPS GTSWSASGIF GRLSQVSEVP LMVVSPAEPH SLAPELQAQR MLAPKRSWGT PQLRLRVLSE TLKSFCLEPE ARLHPAGPAQ LPGEPPPLEE TDWSHSQLLD LGPIDALNFF CEQLRAQQRS SLQEKAAHPH PPEPYTVAPV PDMVVPPPRE HWYHPILRLQ EAKPQRSARS AMRLRGPMRS RLCAGRTLDG PIRTLKLPLP RVEPQPFPLD WPMPPRPLPP RLLQPALQRY FLPADADPDT YS
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