About Methyl-CpG-binding domain protein 3-like 3
Methyl-CpG-binding domain protein 3-like 3 (MBD3L3) is a protein
from Homo sapiens identified by UniProt accession
A6NE82, 208 residues long.
MolForge cross-references it against 0 known binders and
24 disease associations.
Target properties
| Protein name | Methyl-CpG-binding domain protein 3-like 3 |
|---|
| UniProt accession | A6NE82 |
|---|
| Gene | MBD3L3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 208 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (24)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.07
- body height · score 0.06
- fat body mass · score 0.06
- appendicular lean mass · score 0.05
- BMI-adjusted waist-hip ratio · score 0.05
- Red cell distribution width · score 0.05
- whole body water mass · score 0.05
- refractive error measurement · score 0.04
- type 2 diabetes mellitus · score 0.04
- BMI-adjusted waist circumference · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NE82-F1 | alphafold | PREDICTED | 65.83 | — |
Amino-acid sequence (208 residues)
MGEPAFTSFP SPPVLGKLKR NMMPWALQKK REIHMAKAHR RRAARSALPM RLTSCIFRRP VTRIRSHPDN QVRRRKGDEH LEKPQQLCAY RRLQALQPCS SQGEGSSPLH LESVLSILAP GTAGESLDRA GAERVRSPLE PTPGRFPAVA GGPTPGMGCQ LPPPLSGQLV TPADIRRQAR RVKKARERLA KALQADRLAR QAEMLTCR
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