About RCC1 domain-containing protein 1
RCC1 domain-containing protein 1 (RCCD1) is a protein
from Homo sapiens identified by UniProt accession
A6NED2, 376 residues long.
MolForge cross-references it against 0 known binders and
44 disease associations.
Target properties
| Protein name | RCC1 domain-containing protein 1 |
|---|
| UniProt accession | A6NED2 |
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| Gene | RCCD1 |
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| Organism | Homo sapiens |
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| Length | 376 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (44)
Diseases linked to this target (Open Targets).
- Red cell distribution width · score 0.30
- neurodegenerative disease · score 0.24
- body height · score 0.17
- mean corpuscular hemoglobin · score 0.16
- platelet count · score 0.16
- mean platelet volume · score 0.14
- type 2 diabetes mellitus · score 0.13
- platelet component distribution width · score 0.10
- cancer · score 0.08
- glucose measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NED2-F1 | alphafold | PREDICTED | 87.14 | — |
Amino-acid sequence (376 residues)
MAEERPGAWF GFGFCGFGQE LGSGRGRQVH SPSPLRAGVD ICRVSASWSY TAFVTRGGRL ELSGSASGAA GRCKDAWASE GLLAVLRAGP GPEALLQVWA AESALRGEPL WAQNVVPEAE GEDDPAGEAQ AGRLPLLPCA RAYVSPRAPF YRPLAPELRA RQLELGAEHA LLLDAAGQVF SWGGGRHGQL GHGTLEAELE PRLLEALQGL VMAEVAAGGW HSVCVSETGD IYIWGWNESG QLALPTRNLA EDGETVAREA TELNEDGSQV KRTGGAEDGA PAPFIAVQPF PALLDLPMGS DAVKASCGSR HTAVVTRTGE LYTWGWGKYG QLGHEDTTSL DRPRRVEYFV DKQLQVKAVT CGPWNTYVYA VEKGKS
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