About Golgin subfamily A member 6-like protein 4
Golgin subfamily A member 6-like protein 4 (GOLGA6L4) is a protein
from Homo sapiens identified by UniProt accession
A6NEF3, 574 residues long.
MolForge cross-references it against 0 known binders and
29 disease associations.
Target properties
| Protein name | Golgin subfamily A member 6-like protein 4 |
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| UniProt accession | A6NEF3 |
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| Gene | GOLGA6L4 |
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| Organism | Homo sapiens |
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| Length | 574 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (29)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.18
- bipolar disorder · score 0.13
- appendicular lean mass · score 0.12
- BMI-adjusted waist circumference · score 0.12
- body fat percentage · score 0.11
- response to lithium ion · score 0.10
- platelet crit · score 0.10
- BMI-adjusted hip circumference · score 0.08
- neutrophil count · score 0.08
- leukocyte count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NEF3-F1 | alphafold | PREDICTED | 74.69 | — |
Amino-acid sequence (574 residues)
MWPQPRFPPH PAMSEKTQQG KLAAAKKKLK AYWQRKSPGI PAGANRKKKI NGSSPDTATS GGYHSPGDSA TGIYGEGRAS STTLEDLESQ YQELAVALDS SSAIISQLTE NINSLVRTSK EEKKHEIHLV QKLGRSLFKL KNQTAEPLAP EPPAGPSKVE QLQDETNHLR KELESVGRQL QAEVENNQML SLLNRRQEER LREQEERLRE QEERLREQED RLHEQEERLR EQEERLCEQE ERLREHEERL CEQEERLCEQ EERLREQEER LHEQEERLRE QEERLCEQEE RLREQEERLC EQEERLREQE ERLCEQEKLP GQERLLEEVE KLLEQERRQE EQERLLERER LLEEVEKLLE QERQQEEQER LLERERLLEE VEKLLEQERR QEEQERLLER ERLLDEVEEL LDEVEELLEQ ERLRQQDERL WQQETLQELE RLRELERLRE LERMLELGWE ALYEQRAEPR SGFEELNNEN KSTLQLEQQV KELKKSGGAE EPRGSESAAA ARPVAGAPVP QGAWMCGQAG WTPQEHPGLS GEAVGTGEAA GGAGEAACHS FRAAENRELN ITII
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