Uncharacterized protein CXorf65 (CXorf65)

About Uncharacterized protein CXorf65

Uncharacterized protein CXorf65 (CXorf65) is a protein from Homo sapiens identified by UniProt accession A6NEN9, 183 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.

Target properties

Protein name	Uncharacterized protein CXorf65
UniProt accession	A6NEN9
Gene	CXorf65
Organism	Homo sapiens
Length	183 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (8)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.22
attention deficit-hyperactivity disorder 8 · score 0.07
attention deficit hyperactivity disorder · score 0.07
schizophrenia 15 · score 0.07
Phelan-McDermid syndrome · score 0.05
X-linked non-syndromic intellectual disability · score 0.04
lung adenocarcinoma · score 0.01
cancer · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NEN9-F1	alphafold	PREDICTED	82.53	—

Amino-acid sequence (183 residues)

MFIFIKHGDN QQFLVNTNCA VVVLLYYIRS KVKLPKTNTI DLCEQTGKMK MLFLMKPNHA EYASKYLTAR STYYVCKVER GPPGTRLENA YRAFVPLLKN PEPWLLVALR IQCDALERRR IQMLKMKEAK KVVIIEPPAS VPSKQSGRSD KKKSTRKSPT FRNRPDFRKN KGRQLNKTTK QKK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards