About Proline-rich protein 23A
Proline-rich protein 23A (PRR23A) is a protein
from Homo sapiens identified by UniProt accession
A6NEV1, 266 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Proline-rich protein 23A |
|---|
| UniProt accession | A6NEV1 |
|---|
| Gene | PRR23A |
|---|
| Organism | Homo sapiens |
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| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.22
- Keloid · score 0.21
- cortical thickness · score 0.20
- cortical surface area measurement · score 0.20
- brain measurement · score 0.20
- alopecia · score 0.20
- neuroimaging measurement · score 0.16
- androgenetic alopecia · score 0.15
- balding measurement · score 0.11
- 3-hydroxypropylmercapturic acid measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NEV1-F1 | alphafold | PREDICTED | 58.39 | — |
Amino-acid sequence (266 residues)
MGSRPRSPSA FPAPWWGQQP GGPGPAKRLR LEEPAGPEPR VAPSLEDPAG TPAVGALTSI VVLAAGCALR VPLDDVDLVL ELPPTSILRV SLDGHTLILI PEVLLSSVDE RSGAQDDSSA GLEVDVFLGA LREDVVVEQE VFCASVPEIA AQEEAYEEDA DPEFPELQMD SAAGSAAGLY SSARSMFSPY REGPIPEPCA LAPNPSSEGH SPGPFFDPEF RLLEPVPSSP LQPLPPSPRV GSPGPHAHPP LPKRPPCKAR RRLFQE
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