About Anthrax toxin receptor-like
Anthrax toxin receptor-like (ANTXRL) is a protein
from Homo sapiens identified by UniProt accession
A6NF34, 631 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Anthrax toxin receptor-like |
|---|
| UniProt accession | A6NF34 |
|---|
| Gene | ANTXRL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 631 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- prostate carcinoma · score 0.33
- mean corpuscular volume · score 0.25
- facial attractiveness measurement · score 0.24
- Red cell distribution width · score 0.24
- mean corpuscular hemoglobin concentration · score 0.23
- visual perception measurement · score 0.23
- mean corpuscular hemoglobin · score 0.07
- red blood cell density measurement · score 0.02
- erythrocyte count · score 0.02
- schizophrenia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NF34-F1 | alphafold | PREDICTED | 63.12 | — |
Amino-acid sequence (631 residues)
MGSHESLGPY FLVFLLLLLL PPPLFRAGSL RYHGPDWRIF HRLALGSRRA HHHHGPGWRQ HWRQGQAGHR CQGSFDLYFI LDKSGSVNNN WIDLYMWVEE TVARFQSPNI RMCFITYSTD GQTVLPLTSD KNRIKNGLDQ LQKIVPDGHT FMQAGFRKAI QQIESFNSGN KVPSMIIAMT DGELVAHAFQ DTLREAQKAR KLGANVYTLG VADYNLDQIT AIADSPGHVF AVENGFKALR STIDALTSKV CLDVTSVEPS SECVGEPYHV VIHGNGFQNL KKRDEVICRF IFNESTIIDE KPTSIDNNSM NCPGPKLEKP GEEYSIEVSL NKGKTFFKSN VSITSTTCGI FRNWLYFVPL LLLVPLLLCC VWRLCRKQTV KEPPPVQKPE KEPEQEKPPS PPPPPPPPPP PLPPPPPAPV NTCPTVIICC CGCQGVGGMR RIEGNLDTFC DLSHASCHQV PWMCCQSRDQ GRYLSLALAQ SQYAQAPCCP RICFPHSQEC LSLPQAPCSP RMCLRHSREC LALKQARCSP NICLRHSQHS RECLARKQAP CSPRICLRHS PEYFSQAQTL CNPKSCLQPS RECLPLTCSS RCRLPPARCL RPPSRMLPLL SPLLRHTAEP PLSLPPSEPN F
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