Coiled-coil domain-containing protein 182 (CCDC182)

About Coiled-coil domain-containing protein 182

Coiled-coil domain-containing protein 182 (CCDC182) is a protein from Homo sapiens identified by UniProt accession A6NF36, 153 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 182
UniProt accession	A6NF36
Gene	CCDC182
Organism	Homo sapiens
Length	153 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (11)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.10
body height · score 0.09
self reported educational attainment · score 0.09
smoking status measurement · score 0.07
mathematical ability · score 0.07
cognitive function measurement · score 0.07
PHF-tau measurement · score 0.07
chronotype measurement · score 0.05
body mass index · score 0.04
refractive error · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NF36-F1	alphafold	PREDICTED	83.18	—

Amino-acid sequence (153 residues)

MEPLYQAGSI LMTVNTLQGK KMIESGLQSG DFSLSQSWPS CLPPPADLEI LQQKVAGVQR ELEDFKKEAL KSIHYLEDAF CEMNGALVQQ EEQAARVRQR LREEEDRGIV RNKVLTFLLP REKQLREHCK RLEDLLLDRG RDALRATKKS QAD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards