Nuclear protein 2 (NUPR2)

About Nuclear protein 2

Nuclear protein 2 (NUPR2) is a protein from Homo sapiens identified by UniProt accession A6NF83, 97 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Nuclear protein 2
UniProt accession	A6NF83
Gene	NUPR2
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neuroticism measurement · score 0.32
appendicular lean mass · score 0.23
monocyte percentage of leukocytes · score 0.11
amino acid measurement · score 0.10
red blood cell density measurement · score 0.10
threonine measurement · score 0.08
erythrocyte count · score 0.08
serine measurement · score 0.07
sitting height measurement · score 0.07
arterial stiffness measurement · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NF83-F1	alphafold	PREDICTED	72.20	—

Amino-acid sequence (97 residues)

MEAPAERALP RLQALARPPP PISYEEELYD CLDYYYLRDF PACGAGRSKG RTRREQALRT NWPAPGGHER KVAQKLLNGQ RKRRQRQLHP KMRTRLT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards