About EF-hand calcium-binding domain-containing protein 10
EF-hand calcium-binding domain-containing protein 10 (EFCAB10) is a protein
from Homo sapiens identified by UniProt accession
A6NFE3, 127 residues long.
MolForge cross-references it against 0 known binders and
17 disease associations.
Target properties
| Protein name | EF-hand calcium-binding domain-containing protein 10 |
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| UniProt accession | A6NFE3 |
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| Gene | EFCAB10 |
|---|
| Organism | Homo sapiens |
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| Length | 127 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (17)
Diseases linked to this target (Open Targets).
- hereditary neoplastic syndrome · score 0.17
- Inherited cancer-predisposing syndrome · score 0.17
- Acute infantile liver failure-multisystemic involvement syndrome · score 0.15
- mood disorder · score 0.12
- eosinophil count · score 0.12
- Hereditary breast and ovarian cancer syndrome · score 0.12
- hereditary breast ovarian cancer syndrome · score 0.12
- leukocyte count · score 0.11
- basophil count · score 0.10
- self reported educational attainment · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NFE3-F1 | alphafold | PREDICTED | 83.46 | — |
Amino-acid sequence (127 residues)
METSSRELQA AEYLEKHQIK EVVSYLTSAL LFFRPEKPKE YLISLLERLR IAKVTGVAFP FFMDNSNIVA MFEMMDSSGR GTISFVQYKE ALKTLGLCTE DEDLQDDGHK ITLDKFKEEV NKRMKEI
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