Fatty acid-binding protein 12 (FABP12)

About Fatty acid-binding protein 12

Fatty acid-binding protein 12 (FABP12) is a protein from Homo sapiens identified by UniProt accession A6NFH5, 140 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein name	Fatty acid-binding protein 12
UniProt accession	A6NFH5
Gene	FABP12
Organism	Homo sapiens
Length	140 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (20)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.37
high density lipoprotein cholesterol measurement · score 0.09
osteoporosis · score 0.05
Osteoporosis · score 0.05
melorheostosis · score 0.05
dacryocystitis-osteopoikilosis syndrome · score 0.05
12q14 microdeletion syndrome · score 0.04
pyknoachondrogenesis · score 0.04
neoplasm · score 0.04
gnathodiaphyseal dysplasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NFH5-F1	alphafold	PREDICTED	92.76	—

Amino-acid sequence (140 residues)

MIDQLQGTWK SISCENSEDY MKELGIGRAS RKLGRLAKPT VTISTDGDVI TIKTKSIFKN NEISFKLGEE FEEITPGGHK TKSKVTLDKE SLIQVQDWDG KETTITRKLV DGKMVVESTV NSVICTRTYE KVSSNSVSNS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards