Divergent paired-related homeobox (DPRX)

About Divergent paired-related homeobox

Divergent paired-related homeobox (DPRX) is a protein from Homo sapiens identified by UniProt accession A6NFQ7, 191 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Divergent paired-related homeobox
UniProt accession	A6NFQ7
Gene	DPRX
Organism	Homo sapiens
Length	191 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

Short stature · score 0.33
protein measurement · score 0.13
IGF-1 measurement · score 0.02
gonorrhea · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NFQ7-F1	alphafold	PREDICTED	65.83	—

Amino-acid sequence (191 residues)

MPGSEDLRKG KDQMHSHRKR TMFTKKQLED LNILFNENPY PNPSLQKEMA SKIDIHPTVL QVWFKNHRAK LKKAKCKHIH QKQETPQPPI PEGGVSTSVG LRNADTLPRL PNAAHPIGLV YTGHRVPSFQ LILYPNLKVP ANDFIGHRIV HFGCCRDPNI YCLYPILESQ VCAPSFHSGS PACSSNQSRE R

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards