About Cilia- and flagella-associated protein 73
Cilia- and flagella-associated protein 73 (CFAP73) is a protein
from Homo sapiens identified by UniProt accession
A6NFT4, 308 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Cilia- and flagella-associated protein 73 |
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| UniProt accession | A6NFT4 |
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| Gene | CFAP73 |
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| Organism | Homo sapiens |
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| Length | 308 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (8)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.16
- bone density · score 0.16
- Intellectual disability · score 0.12
- platelet count · score 0.03
- body mass index · score 0.03
- immature platelet fraction · score 0.00
- Sjogren syndrome · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NFT4-F1 | alphafold | PREDICTED | 87.98 | — |
Amino-acid sequence (308 residues)
MAVPWEEYFR LALQEKLSTK LPEQAEDHVP PVLRLLEKRQ ELVDADQALQ AQKEVFRTKT AALKQRWEQL EQKERELKGS FIRFDKFLQD SEARRNRALR RAAEERHQAG RREVEALRLW TQLQELRREH ARLQRRLKRL EPCARLLEQA LELLPGFQEV PELVARFDGL AETQAALRLR EREQLAELEA ARARLQQLRD AWPDEVLAQG QRRAQLQERL EAARERTLQW ESKWIQIQNT AAEKTLLLGR SRMAVLNLFQ LVCQHQGQPP TLDIEDTEGQ LEHVKLFMQD LSAMLAGLGQ AEPAAPAS
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