Ig-like V-type domain-containing protein FAM187A…

About Ig-like V-type domain-containing protein FAM187A

Ig-like V-type domain-containing protein FAM187A (FAM187A) is a protein from Homo sapiens identified by UniProt accession A6NFU0, 413 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Ig-like V-type domain-containing protein FAM187A
UniProt accession	A6NFU0
Gene	FAM187A
Organism	Homo sapiens
Length	413 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

primary ciliary dyskinesia · score 0.18
pulse pressure measurement · score 0.10
chronotype measurement · score 0.05
white matter microstructure measurement · score 0.03
nervous system disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NFU0-F1	alphafold	PREDICTED	82.90	—

Amino-acid sequence (413 residues)

MHLALTTVLL WAWGLQAFEI VEKENIFQRT PCPAFLMFEN AAYLADMSFE LPCHCKPEEV PAVVWFYQKH LGSSHTKVLT DFDGRVLTEA AQVRVGSDML TRFSIRMFSL LVFRAQSEDS GLYFCGTRKG DYFYAYDVDI QNSEGMVATF QDKGQEPFAD EYYGHLHVFT TFWEWTPCDR CGVRGEQWRI GLCYLQSPDL SPRYLKAVPD VVSCGSRAVP RKLRTKARDH TPEVLVRSCL VPCEKTKTIR EGVLAIINYV SKVGSRPWVP QVPIQFHQQR LGHGLIISCP GARPEHAVAW DKDRQHLYRT QYLKGVNRSM RVFIDHGNQL HIRFTQLDDR GIYYCWRQGV LVAGFRLGVT SHGHYPASFS DPETRSAVEL TLIGYLLITA VFVTIHFCRC CCYLFHCCPS FSP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Ig-like V-type domain-containing protein FAM187A (FAM187A)