About Oocyte-expressed protein homolog
Oocyte-expressed protein homolog (OOEP) is a protein
from Homo sapiens identified by UniProt accession
A6NGQ2, 149 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Oocyte-expressed protein homolog |
|---|
| UniProt accession | A6NGQ2 |
|---|
| Gene | OOEP |
|---|
| Organism | Homo sapiens |
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| Length | 149 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- female infertility due to zona pellucida defect · score 0.15
- inherited oocyte maturation defect · score 0.14
- Female infertility due to fertilization defect · score 0.08
- female infertility due to oocyte meiotic arrest · score 0.07
- premature ovarian failure 19 · score 0.06
- oocyte maturation defect 9 · score 0.06
- Hydatidiform Mole · score 0.05
- oocyte/zygote/embryo maturation arrest 17 · score 0.05
- oocyte maturation defect 11 · score 0.05
- Rare genetic female infertility · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NGQ2-F1 | alphafold | PREDICTED | 82.10 | — |
Amino-acid sequence (149 residues)
MVDDAGAAES QRGKQTPAHS LEQLRRLPLP PPQIRIRPWW FPVQELRDPL VFYLEAWLAD ELFGPDRAII PEMEWTSQAL LTVDIVDSGN LVEITVFGRP RVQNRVKSML LCLAWFHREH RARAEKMKHL EKNLKAHASD PHSPQDPVA
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