Glutamate-rich protein 4 (ERICH4)

About Glutamate-rich protein 4

Glutamate-rich protein 4 (ERICH4) is a protein from Homo sapiens identified by UniProt accession A6NGS2, 130 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Glutamate-rich protein 4
UniProt accession	A6NGS2
Gene	ERICH4
Organism	Homo sapiens
Length	130 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

prostate carcinoma · score 0.17
testosterone measurement · score 0.12
male reproductive organ cancer · score 0.12
blood protein measurement · score 0.06
Crohn's disease · score 0.05
body height · score 0.04
reticulocyte count · score 0.04
clear cell renal carcinoma · score 0.04
BMI-adjusted hip circumference · score 0.03
balding measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NGS2-F1	alphafold	PREDICTED	78.50	—

Amino-acid sequence (130 residues)

MELWRQLNQA GLVPPGLGPP PQALREVSPV EIPGQTLRTA GADTGGACDS LLWIREELGN LRRVDVQLLG QLCSLGLEMG ALREELVTIL EEEEESSKEE EEDQEPQRKQ EEEHLEACPA PHPPDFEMMI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards