Olfactory receptor 2T8 (OR2T8)

About Olfactory receptor 2T8

Olfactory receptor 2T8 (OR2T8) is a protein from Homo sapiens identified by UniProt accession A6NH00, 312 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Olfactory receptor 2T8
UniProt accession	A6NH00
Gene	OR2T8
Organism	Homo sapiens
Length	312 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.26
neuroblastoma · score 0.21
breast adenocarcinoma · score 0.18
reticulocyte count · score 0.05
Immature Reticulocyte Fraction Measurement · score 0.05
mean platelet volume · score 0.05
platelet count · score 0.05
reticulocyte measurement · score 0.04
platelet component distribution width · score 0.04
mean reticulocyte volume · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NH00-F1	alphafold	PREDICTED	88.71	—

Amino-acid sequence (312 residues)

MENGSYTSYF ILLGLFNHTR AHQVLFMMVL SIVLTSLFGN SLMILLIHWD HRLHTPMYFL LSQLSLMDVM LVSTTVPKMA ADYLTGSKAI SRAGCGAQIF FLPTLGGGEC FLLAAMAYDR YAAVCHPLRY PTLMSWQLCL RMNLSCWLLG AADGLLQAVA TLSFPYCGAH EIDHFFCETP VLVRLACADT SVFENAMYIC CVLMLLVPFS LILSSYGLIL AAVLHMRSTE ARKKAFATCS SHVAVVGLFY GAAIFTYMRP KSHRSTNHDK VVSAFYTMFT PLLNPLIYSV KNSEVKGALT RCMGRCVALS RE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards