About Glycolipid transfer protein domain-containing protein 2
Glycolipid transfer protein domain-containing protein 2 (GLTPD2) is a protein
from Homo sapiens identified by UniProt accession
A6NH11, 291 residues long.
MolForge cross-references it against 0 known binders and
13 disease associations.
Target properties
| Protein name | Glycolipid transfer protein domain-containing protein 2 |
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| UniProt accession | A6NH11 |
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| Gene | GLTPD2 |
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| Organism | Homo sapiens |
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| Length | 291 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (13)
Diseases linked to this target (Open Targets).
- response to statin · score 0.19
- low density lipoprotein cholesterol measurement · score 0.14
- total cholesterol measurement · score 0.13
- blood protein measurement · score 0.07
- serum gamma-glutamyl transferase measurement · score 0.05
- C-X-C motif chemokine 16 measurement · score 0.04
- triglyceride measurement · score 0.03
- Crohn's disease · score 0.01
- atherosclerosis · score 0.01
- Colon Sessile Serrated Adenoma/Polyp · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NH11-F1 | alphafold | PREDICTED | 82.74 | — |
Amino-acid sequence (291 residues)
MGVAARPPAL RHWFSHSIPL AIFALLLLYL SVRSLGARSG CGPRAQPCVP GETAPFQVRQ ESGTLEAPER KQPPCLGPRG MLGRMMRRFH ASLKPEGDVG LSPYLAGWRA LVEFLTPLGS VFAFATREAF TKVTDLEARV HGPDAEHYWS LVAMAAWERR AGLLEQPGAA PRDPTRSSGS RTLLLLHRAL RWSQLCLHRV ATGALGGPDA GVQCSDAYRA ALGPHHPWLV RQTARLAFLA FPGRRRLLEL ACPGATEAEA RAALVRAAGT LEDVYNRTQS LLAERGLLQL A
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