About Golgi apparatus membrane protein TVP23 homolog A
Golgi apparatus membrane protein TVP23 homolog A (TVP23A) is a protein
from Homo sapiens identified by UniProt accession
A6NH52, 213 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Golgi apparatus membrane protein TVP23 homolog A |
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| UniProt accession | A6NH52 |
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| Gene | TVP23A |
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| Organism | Homo sapiens |
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| Length | 213 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (10)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.19
- aspartate aminotransferase measurement · score 0.05
- breast carcinoma · score 0.04
- mean corpuscular volume · score 0.03
- cholesteryl ester measurement · score 0.02
- red blood cell density measurement · score 0.02
- erythrocyte count · score 0.02
- pituitary cancer · score 0.01
- juvenile idiopathic arthritis · score 0.00
- late-onset Parkinson disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NH52-F1 | alphafold | PREDICTED | 79.33 | — |
Amino-acid sequence (213 residues)
MKQALVDDTE DVSLDFGNEE ELAFRKAKIR HPLATFFHLF FRVSAIVTYV SCDWFSKSFV GCFVMVLLLL SLDFWSVKNV TGRLLVGLRW WNQIDEDGKS HWIFEARKVS PNSIAATEAE ARIFWLGLII CPMIWIVFFF STLFSLKLKW LALVVAGISL QAANLYGYIL CKMGGNSDIG KVTASFLSQT VFQTACPGDF QKPGLEGLEI HQH
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