Putative ADP-ribosylation factor-like protein 5C…

About Putative ADP-ribosylation factor-like protein 5C

Putative ADP-ribosylation factor-like protein 5C (ARL5C) is a protein from Homo sapiens identified by UniProt accession A6NH57, 179 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Putative ADP-ribosylation factor-like protein 5C
UniProt accession	A6NH57
Gene	ARL5C
Organism	Homo sapiens
Length	179 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

gut microbiome measurement · score 0.25
22q11.2 deletion syndrome · score 0.04
dilated cardiomyopathy 1I · score 0.04
obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay syndrome · score 0.03
hypoparathyroidism, familial isolated, 2 · score 0.03
Familial isolated hypoparathyroidism · score 0.03
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NH57-F1	alphafold	PREDICTED	84.84	—

Amino-acid sequence (179 residues)

MGQLIAKLMS IFGNQEHTVI IVGLDNEGKT TILYRFLTNE VVHMCPTIGS NVEEIILPKT HFFMWDIVRP EALSFIWNTY YSNTEFIILV IDSTDRDRLL TTREELYKML AHEALQDASV LIFANKQDVK DSMRMVEISH FLTLSTIKDH SWHIQGCCAL TREGLPARLQ WMESQAAAN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Putative ADP-ribosylation factor-like protein 5C (ARL5C)