About Putative D-dopachrome decarboxylase-like protein
Putative D-dopachrome decarboxylase-like protein (DDTL) is a protein
from Homo sapiens identified by UniProt accession
A6NHG4, 134 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Putative D-dopachrome decarboxylase-like protein |
|---|
| UniProt accession | A6NHG4 |
|---|
| Gene | DDTL |
|---|
| Organism | Homo sapiens |
|---|
| Length | 134 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.25
- protein measurement · score 0.22
- IGF-1 measurement · score 0.20
- sex hormone-binding globulin measurement · score 0.15
- macrophage migration inhibitory factor measurement · score 0.13
- insulin like growth factor measurement · score 0.12
- triglyceride measurement · score 0.12
- urinary S-phenylmercapturic acid measurement · score 0.11
- serum gamma-glutamyl transferase measurement · score 0.11
- serum alanine aminotransferase measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NHG4-F1 | alphafold | PREDICTED | 73.25 | — |
Amino-acid sequence (134 residues)
MPFLELDTNL PANRVPAGLE KRLCAAAASI LGKPADRVNV TVRPGLAMAL SGSTEPCAQL SISSIGVVGT AEDNRSHSAH FFEFLTKELA LGQDRFPTVL STSPAAHGGP RCPGEIIEGK KSCLNEEALF IYFI
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