About Zinc finger protein 860
Zinc finger protein 860 (ZNF860) is a protein
from Homo sapiens identified by UniProt accession
A6NHJ4, 632 residues long.
MolForge cross-references it against 0 known binders and
18 disease associations.
Target properties
| Protein name | Zinc finger protein 860 |
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| UniProt accession | A6NHJ4 |
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| Gene | ZNF860 |
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| Organism | Homo sapiens |
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| Length | 632 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (18)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.24
- triglyceride measurement · score 0.07
- sleep duration · score 0.07
- colorectal adenocarcinoma · score 0.04
- type 2 diabetes mellitus · score 0.02
- gonorrhea · score 0.01
- hyperuricemia · score 0.01
- metabolic syndrome · score 0.01
- Leishmaniasis · score 0.01
- diffuse large B-cell lymphoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NHJ4-F1 | alphafold | PREDICTED | 63.39 | — |
Amino-acid sequence (632 residues)
MLREEAAQKR KEKEPGMALP QGHLTFRDVA IEFSLEEWKC LDPTQRALYR AMMLENYRNL HSVDISSKCM MKKFSSTAQG NTEVDTGTLE RHESHHIGDF CFQKIGKDIH DFEFQWQEDK RNSHEATMTQ IKKLTGSTDR YDRRHPGNKP IKDQLGLSFH SHLPELHIFQ TKGKVGNQVE KSINDASSVL TSQRISSRPK IHISNNYENN FFHSSLLTLK QEVHIREKSF QCNESGKAFN CSSLLRKHQI IYLGGKQYKC DVCGKVFNQK RYLACHHRCH TGEKPYKCNE CGKVFNQQSN LASHHRLHTG EKPYKCEECD KVFSRKSNLE RHRRIHTGEK PYKCKVCEKA FRRDSHLTQH TRIHTGEKPY KCNECGKAFS GQSTLIHHQA IHGIGKLYKC NDCHKVFSNA TTIANHWRIH NEERSYKCNK CGKFFRRRSY LVVHWRTHTG EKPYKCNECG KTFHHNSALV IHKAIHTGEK PYKCNECGKT FRHNSALVIH KAIHTGEKPY KCNECGKVFN QQATLARHHR LHTGEKPYKC EECDTVFSRK SHHETHKRIH TGEKPYKCDD FDEAFSQASS YAKQRRIHMG EKHHKCDDCG KAFTSHSHRI RHQRIHTGQK SYKCHKRGKV FS
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