Tubulin alpha chain-like 3 (TUBAL3)

About Tubulin alpha chain-like 3

Tubulin alpha chain-like 3 (TUBAL3) is a protein from Homo sapiens identified by UniProt accession A6NHL2, 446 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.

Target properties

Protein name	Tubulin alpha chain-like 3
UniProt accession	A6NHL2
Gene	TUBAL3
Organism	Homo sapiens
Length	446 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (42)

Diseases linked to this target (Open Targets).

viral disease · score 0.46
head and neck squamous cell carcinoma · score 0.23
esophageal cancer · score 0.23
gastric adenocarcinoma · score 0.23
breast adenocarcinoma · score 0.23
triglyceride measurement · score 0.11
sleep duration · score 0.09
IGF-1 measurement · score 0.08
sex hormone-binding globulin measurement · score 0.08
alkaline phosphatase measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NHL2-F1	alphafold	PREDICTED	90.89	—

Amino-acid sequence (446 residues)

MRECLSIHIG QAGIQIGDAC WELYCLEHGI QPNGVVLDTQ QDQLENAKME HTNASFDTFF CETRAGKHVP RALFVDLEPT VIDGIRTGQH RSLFHPEQLL SGKEDAANNY ARGRYSVGSE VIDLVLERTR KLAEQCGGLQ GFLIFRSFGG GTGSGFTSLL MERLTGEYSR KTKLEFSVYP APRISTAVVE PYNSVLTTHS TTEHTDCTFM VDNEAVYDIC HRKLGVECPS HASINRLVVQ VVSSITASLR FEGPLNVDLI EFQTNLVPYP RIHFPMTAFA PIVSADKAYH EQFSVSDITT ACFESSNQLV KCDPRLGKYM ACCLLYRGDV VPKEVNAAIA ATKSRHSVQF VDWCPTGFKV GINNRPPTVM PGGDLAKVHR SICMLSNTTA IVEAWARLDH KFDLMYAKRA FLHWYLREGM EEAEFLEARE DLAALERDYE EVAQSF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards