About Nuclear pore complex-interacting protein family member B15
Nuclear pore complex-interacting protein family member B15 (NPIPB15) is a protein
from Homo sapiens identified by UniProt accession
A6NHN6, 443 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Nuclear pore complex-interacting protein family member B15 |
|---|
| UniProt accession | A6NHN6 |
|---|
| Gene | NPIPB15 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 443 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (14)
Diseases linked to this target (Open Targets).
- diet measurement · score 0.14
- systolic blood pressure · score 0.09
- mood instability measurement · score 0.08
- sleep apnea · score 0.04
- vital capacity · score 0.02
- alcohol consumption measurement · score 0.02
- FEV/FVC ratio · score 0.02
- leukocyte count · score 0.02
- Ataxia-telangiectasia · score 0.02
- prostate carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NHN6-F1 | alphafold | PREDICTED | 49.61 | — |
Amino-acid sequence (443 residues)
MRLRFWLLIW LLLGFISHQP TPVINSLAVY RHRETDFGVG VRDHPGQHGK TPSPQKLDNL IIIIIGFLRR DTFTILFCTS YLCVSFLKTI FWSRNGHDGS TDVQQRAWRS NRSRQKGLRS ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINRHD KINGKRKTAR KQKMFQRAQE LRRRAEDYHK CKIPPSARKP LCNWVRMAAA EHRHSSGLPC WPYLTAEALK NRMGRQPPPP TQQHSITDNS LSLKTPPECL LHPLPPSVDD NIKECPLAPL PPSVDDNLKE YLLVPLPPSP LPPSVDDNLK DCLFVPLPPS PLPPSVDDNL KTPPLATQEA EAEKPPKPKR WRVDEVEQSP KPKRRRADEV EQSPKPKRQR EAEAQQLPKP KRRRLSKLRT RHCTQAWAIR INPWVEKKKK IKKQNKTHAP KTN
Explore Nuclear pore complex-interacting protein family member B15 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets