About Homeobox protein HMX3
Homeobox protein HMX3 (HMX3) is a protein
from Homo sapiens identified by UniProt accession
A6NHT5, 357 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Homeobox protein HMX3 |
|---|
| UniProt accession | A6NHT5 |
|---|
| Gene | HMX3 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 357 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- sleep duration · score 0.26
- body height · score 0.22
- lung volume · score 0.19
- vital capacity · score 0.18
- serum urea measurement · score 0.18
- handedness · score 0.17
- alcohol consumption measurement · score 0.16
- adolescent idiopathic scoliosis · score 0.16
- IGF-1 measurement · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NHT5-F1 | alphafold | PREDICTED | 60.82 | — |
Amino-acid sequence (357 residues)
MPEPGPDAAG TASAQPQPPP PPPPAPKESP FSIKNLLNGD HHRPPPKPQP PPRTLFAPAS AAAAAAAAAA AAAKGALEGA AGFALSQVGD LAFPRFEIPA QRFALPAHYL ERSPAWWYPY TLTPAGGHLP RPEASEKALL RDSSPASGTD RDSPEPLLKA DPDHKELDSK SPDEIILEES DSEESKKEGE AAPGAAGASV GAAAATPGAE DWKKGAESPE KKPACRKKKT RTVFSRSQVF QLESTFDMKR YLSSSERAGL AASLHLTETQ VKIWFQNRRN KWKRQLAAEL EAANLSHAAA QRIVRVPILY HENSAAEGAA AAAAGAPVPV SQPLLTFPHP VYYSHPVVSS VPLLRPV
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