Tripartite motif-containing protein 64B (TRIM64B)

About Tripartite motif-containing protein 64B

Tripartite motif-containing protein 64B (TRIM64B) is a protein from Homo sapiens identified by UniProt accession A6NI03, 449 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

Target properties

Protein name	Tripartite motif-containing protein 64B
UniProt accession	A6NI03
Gene	TRIM64B
Organism	Homo sapiens
Length	449 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (13)

Diseases linked to this target (Open Targets).

smoking status measurement · score 0.12
homocysteine measurement · score 0.04
lean body mass · score 0.03
fat body mass · score 0.03
adolescent idiopathic scoliosis · score 0.03
body mass index · score 0.03
body fat percentage · score 0.03
sunburn · score 0.03
pulse pressure measurement · score 0.03
hair colour measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NI03-F1	alphafold	PREDICTED	85.07	—

Amino-acid sequence (449 residues)

MDSDDLQVFQ NELICCICVN YFIDPVTIDC GHSFCRPCLC LCSEEGRAPM RCPSCRKTSE KPNFNTNLVL KKLSSLARQT RPQNINSSDN ICVLHEETKE LFCEADKRLL CGPCSESPEH MAHSHSPIGW AAEECREKLI KEMDYLWEIN QETRNNLNQE TSTFHSLKDY VSVRKRIITI QYQKMPIFLD EEEQRHLQAL EREAEELFQQ LQDSQVRMTQ HLERMKDMYR ELWETCHMPD VVLLQDVRNV SARTDLAQMQ KPQPVNPELT SWCITGVLDM LNNFRVDSAL STEMIPCYIS LSEDVRYVIF GDDHLSAPTD PQGVDSFAVW GAQAFTSGKH YWEVDVTLSS NWILGVCRDS RTADANFVID SDERFFLISS KRSNHYSLST NSPPLIQYVQ RPLGRVGVFL DYDNGSVSFF DVSKGSLIYG FPPSSFSSPL RPFFCFGCT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards