About Mesogenin-1
Mesogenin-1 (MSGN1) is a protein
from Homo sapiens identified by UniProt accession
A6NI15, 193 residues long.
MolForge cross-references it against 0 known binders and
19 disease associations.
Target properties
| Protein name | Mesogenin-1 |
|---|
| UniProt accession | A6NI15 |
|---|
| Gene | MSGN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (19)
Diseases linked to this target (Open Targets).
- FEV/FVC ratio · score 0.04
- forced expiratory volume · score 0.04
- vital capacity · score 0.04
- body fat percentage · score 0.04
- isolated Klippel-Feil syndrome · score 0.04
- bone density · score 0.04
- urate measurement · score 0.04
- diaphanospondylodysostosis · score 0.03
- autosomal recessive spondylocostal dysostosis · score 0.03
- autosomal dominant spondylocostal dysostosis · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-A6NI15-F1 | alphafold | PREDICTED | 66.34 | — |
Amino-acid sequence (193 residues)
MDNLRETFLS LEDGLGSSDS PGLLSSWDWK DRAGPFELNQ ASPSQSLSPA PSLESYSSSP CPAVAGLPCE HGGASSGGSE GCSVGGASGL VEVDYNMLAF QPTHLQGGGG PKAQKGTKVR MSVQRRRKAS EREKLRMRTL ADALHTLRNY LPPVYSQRGQ PLTKIQTLKY TIKYIGELTD LLNRGREPRA QSA
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