Coiled-coil domain-containing protein 69 (CCDC69)

About Coiled-coil domain-containing protein 69

Coiled-coil domain-containing protein 69 (CCDC69) is a protein from Homo sapiens identified by UniProt accession A6NI79, 296 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	Coiled-coil domain-containing protein 69
UniProt accession	A6NI79
Gene	CCDC69
Organism	Homo sapiens
Length	296 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

monocyte count · score 0.44
Red cell distribution width · score 0.43
leukocyte count · score 0.42
myeloid white cell count · score 0.39
neutrophil count · score 0.39
lymphocyte count · score 0.38
FEV/FVC ratio · score 0.32
chronic obstructive pulmonary disease · score 0.28
neurodegenerative disease · score 0.24
smoking status measurement · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-A6NI79-F1	alphafold	PREDICTED	84.58	—

Amino-acid sequence (296 residues)

MGCRHSRLSS CKPPKKKRQE PEPEQPPRPE PHELGPLNGD TAITVQLCAS EEAERHQKDI TRILQQHEEE KKKWAQQVEK ERELELRDRL DEQQRVLEGK NEEALQVLRA SYEQEKEALT HSFREASSTQ QETIDRLTSQ LEAFQAKMKR VEESILSRNY KKHIQDYGSP SQFWEQELES LHFVIEMKNE RIHELDRRLI LMETVKEKNL ILEEKITTLQ QENEDLHVRS RNQVVLSRQL SEDLLLTREA LEKEVQLRRQ LQQEKEELLY RVLGANASPA FPLAPVTPTE VSFLAT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards